NT-proBNP as a Predictive Biomarker for Contrast-Induced Nephropathy in ACS Patients Undergoing Coronary Angiogram – An Observational Study

Objectives: 1. To assess the value of baseline NTproBNP at admission and to determine levels serum creatinine 48 hours 72 after procedure for evidence contrast-induced nephropathy (CIN) patients undergoing CAG. 2. evaluate relationship between values CIN. Materials Methods: This is an observational study performed June 2021-November 2021 Nizams Institute Medical Sciences in 75 diagnosed with ACS. we assessed role nt pro bnp as a predictive biomarker diagnosis contrast induced ACS coronary angiography. Serum repeated h post compared baseline. Results: Spearman’s correlation test was used NT-proBNP ejection fraction on 2D echo. The rho (-0.69) suggestive strong negative correlation. P & lt; 0.001 making it statistically significant. Simple linear regression analysis predict by percentage among patients, showed that, every 1% decrease fraction, will significantly increase 102.90 pg/mL 0.001. Wilcoxon Signed Rank compare 48/72 angiography contrast, incidence acute kidney injury (AKI) shown resulting 0.001, thus ROC curve establish association marker AKI shows cut off gt;1670 has sensitivity 81.82% specifity 98.44% significant Conclusion: It observed that >1670 prior procedure, associated risk development nephropathy. Measurement pre aids identifying population developing